Most Commonly Used Psychedelic Medicines

The most common substances and their general effects and properties, as well as potential harms and therapeutic uses. From the National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health.

Ketamine

• General effects and properties:
  NMDA Receptor
  Feelings of deep relaxation or dissociation

  Euphoria

  Heightened Senses
  Perceptual alteration
  Enhanced empathy and sociability

  Safely revisiting past memories or trauma

• Potential harms:
  Bladder Damage- Ketamine Cystitis

  Hypertension & Tachycardia during treatment
  Cognitive Difficulties- specifically learning new tasks

  Not safe for fetuses

  Dissociation

  Sedation

  Nausea/ Vomiting

• Potential therapeutic uses:
  PTSD

  Depression

  Anxiety

  Substance Use Disorders

  OCD

  Bipolar Disorder

  Suicidal thoughts

LSD

• General effects and properties:
  5-HT2A (serotonin) agonist of pyramidal neurons
  Dizziness, weakness, tremors, paresthesia
  Altered consciousness (visions, auditory distortions, ideations)
  Altered mood (happy, sad, fearful, irritable)
  Distorted sense of space, time

• Potential harms:
  Psychosis
  Hallucinogen persisting perception disorder

• Potential therapeutic uses:
  Addiction (alcohol)
  Anxiety associated with terminal illness

Psilocybin

• General effects and properties:
  5-HT2A (serotonin) agonist of pyramidal neurons
  Dizziness, weakness, tremors, paresthesia
  Altered consciousness (visions, auditory distortions, ideations)
  Altered mood (happy, sad, fearful, irritable)
  Distorted sense of space, time

• Potential harms:
  Psychosis
  Hallucinogen persisting perception disorder

• Potential therapeutic uses:
  Addiction (tobacco, alcohol)
  Anxiety associated with terminal illness

(DMT) Ayahuasca

• General effects and properties:
  5-HT2A (serotonin) agonist of pyramidal neurons
  Dizziness, weakness, tremors, paresthesia
  Nausea, emesis
  Altered consciousness (visions, auditory distortions, ideations)
  Altered mood (happy, sad, fearful, irritable)
  Distorted sense of space, time

• Potential harms:
  Psychosis
  Serotonin syndrome and other dangers from medication interactions due to monoamine oxidase inhibitory activity

• Potential therapeutic uses:
  Addiction (alcohol, cocaine, tobacco)
  Depression, anxiety

Mescaline

• General effects and properties:
  5-HT2A (serotonin) agonist of pyramidal neurons
  Dizziness, weakness, tremors, paresthesia
  Altered consciousness (visions, auditory distortions, ideations)
  Altered mood (happy, sad, fearful, irritable)
  Distorted sense of space, time

• Potential harms:
  Psychosis

• Potential therapeutic uses:
  Addiction (alcohol)

MDMA

• General effects and properties:
  Serotonin, dopamine and noradrenaline agonist
  Euphoria
  Arousal
  Perceptual alteration
  Enhanced empathy and sociability

• Potential harms:
  Potential neurocognitive deficits (memory impairment)
  Sleep disruption
  Short-term depression

• Potential therapeutic uses:
  PTSD

 Mindful Monarch Therapy & Consulting does not provide psychoactive or controlled substances. We are not spiritual guides or scientists. We do not conduct “underground” (illegal) psychedelic services. Please use your discretion to ensure our services meet your needs.